Assuntos
Síndrome de Asperger/complicações , Fibroma/etiologia , Fricção , Neoplasias Cutâneas/etiologia , Adolescente , Dedos , Humanos , MasculinoRESUMO
We present a family with Buschke-Ollendorff syndrome presenting as elastic tissue naevi without evidence of osteopoikilosis. We discuss the variable expression of this syndrome in other families previously reported in the literature, the association of various connective tissue abnormalities and their correlation with the pathogenesis of this interesting condition.
Assuntos
Doenças do Tecido Conjuntivo/genética , Tecido Elástico , Nevo/genética , Doenças do Tecido Conjuntivo/patologia , Tecido Elástico/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nevo/patologia , Linhagem , SíndromeRESUMO
We report the case of a woman who had pain in both heels which was exacerbated by long periods of exercise. On examination, there were small flesh-coloured papules which appeared over the medial and lateral aspects of the heels only on weight bearing. Coincidentally, she was noted to have larger flesh-coloured papules over the anterior surface of the shins. The diagnoses of painful piezogenic pedal papules and bilateral tibialis anterior muscle herniation, respectively, were made. After many attempts to control the pain, a course of electro-acupuncture was commenced. A good subjective clinical response was achieved which has been maintained by fortnightly treatments. We discuss the prevalence, pathogenesis and treatment of painful piezogenic pedal papules. We believe that our patient is the first to have 'herniations' at both heel and shin sites and the first to have successful sustained pain relief for painful piezogenic pedal papules.
Assuntos
Analgesia por Acupuntura/métodos , Eletroacupuntura , Dermatoses do Pé/terapia , Adulto , Exercício Físico , Feminino , Dermatoses do Pé/patologia , Hérnia/patologia , Humanos , Dermatoses da Perna/patologiaRESUMO
We report the case of a 39-year-old woman with a persistent congenital vascular lesion, which unusually is continuing to enlarge. Histologically, the lesion is a thin-walled haemangioma with numerous mast cells. Currently, the precise mechanism of vessel proliferation in such lesions is unknown, but it is important in the pathogenesis of both haemangiomas and other dermatological conditions, as well as in wound healing and the formation of tumour metastases. We discuss various angiogenic factors with particular reference to the putative role of the mast cell in the pathogenesis of haemangiomas.
Assuntos
Hemangioma/congênito , Neoplasias Cutâneas/congênito , Adulto , Feminino , Hemangioma/patologia , Humanos , Prurido/complicações , Neoplasias Cutâneas/patologiaRESUMO
Sweet's syndrome is an acute neutrophilic dermatosis frequently found in association with other conditions, particularly inflammatory and neoplastic disease. We report here a patient who developed the condition 2 years after the diagnosis of non-Hodgkin's lymphoma (NHL), in this case affecting a tonsil, the thirteenth report of such an association. We discuss the diagnosis, investigation and management of Sweet's syndrome in the context of the current case.
Assuntos
Linfoma não Hodgkin/complicações , Síndrome de Sweet/complicações , Neoplasias Tonsilares/complicações , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. We report a case in which identical T-cell clones were identified in both patch and tumour stage lesions and in which the tumorous deposits, containing CD30-positive cells, regressed spontaneously. We discuss the differential diagnosis of the tumorous lesions and the spectrum of CD30-positive proliferative T-cell disorders.
